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Now Available: Innovators Under 35 2013 See The 2013 List »

Trey Ideker, 33

Defining and advancing systems biology

University of California, San Diego

As a graduate student, Trey Ideker published a paper that helped define the discipline of systems biology. His research goals today reflect those of the entire field: to integrate the myriad data that researchers can collect about a cell into coherent computer models. As an assistant professor of bioengineering, Ideker is not only improving these models but employing them in biological discovery. For instance, he is looking for protein networks uniquely present in pathogenic organisms; these could make good drug targets. He hopes that, ultimately, systems-derived models will let researchers simulate how potential drugs will affect the body -- long before the compounds are tested in humans.

2005 TR35 Winners

Thijn Brummelkamp

Silencing the genes that cause cancer

Martha Bulyk

Discovering how genes are regulated

Matthew DeLisa

Delivering more medicine from microbes

Kevin Eggan

Using cloning to study degenerative diseases

Paul Hergenrother

Discovering drugs that defy convention

Trey Ideker

Defining and advancing systems biology

Hang Lu

Designing microfluidic chips to study cells

Melissa Mahoney

Making materials to treat brain damage

Daniel Riskin

Developing devices for wound closure and early heart-attack intervention.

Shiladitya Sengupta

Delivering drugs to cancer cells

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