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Now Available: Innovators Under 35 2013 See The 2013 List »

Melissa Mahoney, 32

Making materials to treat brain damage

University of Colorado at Boulder

Nerve cell transplants offer tremendous promise for patients who are suffering the effects of stroke, or from Parkinsons disease or other neurodegenerative illnesses. But experiments in rodents showed that about 95 percent of cells transplanted into the brain die before they can help the recipient. Melissa Mahoney is working to develop hydrogel materials that can house the cells, protecting them and supplying them with proteins that encourage their growth. In collaboration with scientists at the University of Colorado at Denvers Health Sciences Center, Mahoney, an assistant professor of chemical engineering, plans to test these cell-loaded gels in rats within the next year.

2005 TR35 Winners

Thijn Brummelkamp

Silencing the genes that cause cancer

Martha Bulyk

Discovering how genes are regulated

Matthew DeLisa

Delivering more medicine from microbes

Kevin Eggan

Using cloning to study degenerative diseases

Paul Hergenrother

Discovering drugs that defy convention

Trey Ideker

Defining and advancing systems biology

Hang Lu

Designing microfluidic chips to study cells

Melissa Mahoney

Making materials to treat brain damage

Daniel Riskin

Developing devices for wound closure and early heart-attack intervention.

Shiladitya Sengupta

Delivering drugs to cancer cells

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