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Now Available: Innovators Under 35 2013 See The 2013 List »

Vipul Ved Prakash, 25

Developed free and commercial software filters that fight spam

Cloudmark

In 1997, Vipul Ved Prakash dropped out of Delhi University “for want of undisturbed coding time,” as he puts it. He then cofounded Sense/Net, one of India’s first privately owned Internet service providers, but soon encountered the scourge of spam. Customers paying by the minute for their connections complained they were wasting time deleting inwanted e-mail. So Prakash developed Vipul’s Razor, a spam-fighting, opensource software tool available online for free. Thousands of users downloaded the “collaborative filter” program, which allowed them to keep messages or move them into spam folders. Vipul’s Razor transmitted those decisions to a central server, and if a majority of users discarded a given message, it would therefore be blocked for the entire group. After moving from New Delhi to California in 2000, Prakash worked for a time at Napster and then cofounded Cloudmark with Jordan Ritter, Napster’s former software chief. The San Francisco startup adapted Vipul’s Razor into a tool called SpamNet that today boasts 500,000 users. Initially free, it now costs $3.99 per month. “When a new person joins,” Prakash says, “they get the benefit of the entire community.” Cloudmark also markets Authority, a corporate version of SpamNet.

2003 TR35 Winners

Guillermo Ameer

Synthesized "biorubbers" that could replace damaged heart and lung tissue and rebuild blood vessels

Helene Andersson

Produces portable, inexpensive, microprocessor-size labs for research and industry

John Apostolopoulos

Develops ways to improve the security of streaming video on the Net

Scott Backhaus

Invented a novel, high-efficiency engine powered by sound waves

Zhenan Bao

Fabricates organic semiconductors used in flexible and cheap electronic devices

Geoffrey Barrows

Gives unmanned reconnaissance planes insect vision

Serafim Batzoglou

Devises powerful tools for assembling and analyzing genomes

Brian Behlendorf

Sparked the widespread development of Web servers, mainstreaming the nascent Web

Sangeeta Bhatia

Uses microchip-manufacturing tools to build artificial livers

Marcela Bilek

Designs coatings to improve implanted medical devices and industrial tools

Daniel Bond

Turns sea muck into fuel cell power plants

Alexis Borisy

Believes that combining different drugs could yield better ways to fight disease

Jud Bowman

Wrote software that is accelerating the expansion of wireless networking

Michael Bowman

Builds microturbines that could become the power plant of choice in many settings

Cynthia Breazeal

Constructs robots whose expressive faces convey humanlike emotions

Colin Bulthaup

Developed new fabrication methods that could slash the cost of chip manufacturing

Karen Burg

Engineered a minimally invasive process to rebuild tissue for breast cancer survivors

Eugene Chan

Aims to speed genome sequencing with a machine that reads DNA letter by letter

Ian Clarke

Pioneered software that delivers Web files quickly, anonymously

Lorrie Cranor

Leads the global effort to improve privacy practices and tools on the Web

Bassil Dahiyat

Designs proteins from scratch to create new medicine

Benjamin G. Davis

Manipulates biological sugars for more precise drug delivery

Andre DeHon

Designs architectures needed to build practical molecular computers

Xiangfeng Duan

Transforms nanowires into incredibly small transistors for powerful, flexible computers

Christophe Echeverri

Develops fast, automated processes for figuring out genes functions

Stephen Empedocles

Formulates business strategy for one of nanotechs leading startups

Vladislav Gavrilets

Designs flight control technology that could lead to unmanned autonomous helicopters

Scott Gaynor

Devises processes used to make polymers with improved properties

Michael E. Gertner

Set out to improve the tiny devices that keep once blocked arteries open

Daniel Gottesman

Works to improve quantum computers so they can speed drug design and perform other massive computing tasks

Jay Groves

Patented a lab-on-a-chip to investigate call proteins that cause diseases

Kathryn Guarini

Fabricates three-dimensional integrated circuits that could vastly increase computer power

Vic Gundotra

Sparked Microsofts change to .Net

Cary Gunn

Shrinks optical circuitry to speed transmissions on phone and Internet networks

Justin Hanes

Creates systems for delivering drugs to where theyre needed in the body

Andrew Heafitz

Invented inexpensive rocket-based surveillance systems

Jason Hill

Wrote software that allows hundreds of minute wireless sensors to communicate better

Steven Hofmeyr

Devised software that roots out security threats to a networks operating system

Mike Horton

Engineers tiny sensors that can be spread like crumbs around a battlefield or factory

Meg Hourihan

Sparked the rise of the popular Web-based journals known as blogs

Ayanna Howard

Writes programs that more intelligently guide actions of robots

Yu Huang

Fashions three-dimensional grids of nanowires that act as electronic circuits

Paul Q. Judge

Wrote software that stops spam and viruses before they enter a network

Jordan Katrine

Makes higher-density hard drives using magnetic nanomaterials

Andre Koltermann

Speeds protein evolution to improve detergents, medicines, and foods

Krishna Kumar

Improves the stability and effectiveness of protein-based drugs

Erin Lavik

Helped paralyzed rats walk again and aims to do the same for people

Kevin Lee

Integrates photonics and electronics on chips to speed telecommunications

Rasmus Lerdorf

Invented a server language that brought live data to the Web

Desmond Lim

Develops high-volume manufacturing lines for making optical chips into commodities

Lih Y. Lin

Built micromirror switches for faster, all-optical telecommunications networks

Xiangjun Liu

Maps gene variations that could warn of future disease

Anthony Lowman

Packs insulin into gel pills that could replace injections for diabetes patients

David M. Lynn

Synthesizes polymers that are better able to deliver therapeutic genes

Gavin Macbeath

Unravels complex biological systems in his search for new drugs

Paul Meyer

Brings database and Web-like services to remote areas through touch-tone phones

David A. Muller

Images the individual atom that are critical to a transistors electronic properties

Yasunobu Nakamura

Achieved a breakthrough that could help make quantum computing a reality

Balaji Narasimhan

Devises time-release polymers to replace multiple vaccine injections

Michael OConnor

Designed an automated tractor steering system that is saving farmers bushels of money

Ravikanth Pappu

Fights credit card forgery with glass-bead “keys”

Sanjay Parekh

Develops software that lets companies tailor services to their customers locations

Joe Pompei

Delivers "spotlights" of sound for use in concerts, museums, and automobiles

Jovan Popovic

Makes simpler, more powerful animation tools for novices and professionals

Vipul Ved Prakash

Developed free and commercial software filters that fight spam

Nimmi Ramanujam

Uses light to help make diagnosing breast cancer and cervical cancer faster, more accurate and less invasive

Ainissa G. Ramirez

Formulated an advanced universal solder for electronics and optics

Thomas Reardon

Tailors Internet application to cell phones

Christian Rehtanz

Adds smarts to high-voltage power lines so they can deliver more electricity

Torsten Reil

Employs simulations of human movement to create realistically animated characters

Heike Riel

Built large, bright, organic video displays using materials dismissed by contemporaries

Maximilian Riesenhuber

Programs computers to recognize objects the way the human brain does

Linda Rottenberg

Helps entrepreneurs in emerging nations turn innovations into business

Shuvo Roy

Builds tiny machines that can warn of impending heart attack and monitor healing after surgery

Ram Samudrala

Wrote algorithms that can predict the functions of proteins from the sequence of a genome

Ted Sargent

Fashions photonic circuits that could speed voice and data to homes

Christophe Schilling

Transforms microbes into fine-tuned manufacturing machines

Mark Schnitzer

Sheds light on the functioning of individual brain cells

Mijail Serruya

Connects brains directly to computers int he hope of helping paralyzed people communicate and control robotic aids

Tim Sibley

Serves up customized audio and video gems

Micah Siegel

Transforms research from universities and national labs into successful startups

Rueben Singh

Provides support services and startup money for entrepreneurs

Manfred Stefener

Constructs small fuel cells to efficiently power laptop computers

Claire Tomlin

Writes software that could alleviate air congestion and lead to far fewer delays at airports

Giovanni Traverso

Came up with a noninvasive alternative to colonoscopy

Stephen Turner

Built a tiny device that greatly speeds up DNA sequencing

Rita Vanbever

Wants to make treating diabetes as easy as breathing

Alex Vasilescu

Transforms computers ability to recognize human faaces

S. Travis Waller

Writes algorithms that determine why traffic jams form and how to ease them

Martin Wattenberg

Simplifies peoples electronic lives with graphical data management

Ralf Wehrspohn

Fabricates nanotube crystals that can route optical telecommunications signals faster than competing chips

Ron Weiss

Programs living cells to sense toxins ot create replacement tissues

Jennifer West

Synthesizes blood vessels that could reduce the trauma of heart surgery

Andrew Wheeler

Builds wireless sensor networks that improve industrial efficiency

Lorraine Wheeler

Codes software that makes handheld computers handier

Evan Williams

Fueled the expansion of blogs across the Web

Tsuyoshi Yamamoto

Builds brain-imaging machines that are faster and cheaper than magnetic-resonance imaging equipment

Peidong Yang

Assembles nanowires that could revolutionize lasers and computers

Jennifer Yates

Wrote software widely adopted by the telecom industry that speeds up optical networks

Daphne Zohar

Spots promising biotech work and helps build new companies to commercialize it

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