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Now Available: Innovators Under 35 2013 See The 2013 List »

Stephen Quake, 32

Materials

Caltech

The biotech industry dreams of automating millions of biological experiments on mass-produced chips. Colleagues say Steve Quake has the creativity, intellect and ambition to make it happen. When Quake was a Stanford University postdoc, he investigated the behavior of biological polymers. After becoming a Caltech professor he developed his first micro-fabricated tools, which use electric fields to sort cells and manipulate DNA molecules. Soon thereafter, Quake used soft lithography to build the first set of microvalves and pumps practical enough to be mass-produced, a key step toward developing the hotly anticipated chips. In 1999,Quake and some former college buddies founded San Francisco-based Fluidigm to supply his patented equipment and intellectual property to life science and pharmaceutical companies. Fluidigm has received $50 million in capital and recently signed a deal to supply GlaxoSmithKline.Now a tenured professor, Quake divides his time between researching the structure and function of proteins and devising more-sophisticated microfluidic tools.

2002 TR35 Winners

Ewan Birney

Biotechnology

Fiona Brinkman

Biotechnology

Chris Burge

Biotechnology

Benjamin Cravatt

Biotechnology

Nathaniel David

Biotechnology

Susan Hagness

Medicine

Derek Hansford

Materials

J. Joseph Kim

Medicine

Steven Laken

Medicine

Kelvin Lee

Medicine

Milan Mrksich

Materials

Stephen OConnor

Biotechnology

Alexander Olek

Biotechnology

Vijay Pande

Biotechnology

Stephen Quake

Materials

David Sabatini

Biotechnology

John Santini

Medicine

David Schaffer

Medicine

Christoph Westphal

Biotechnology

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