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Biomedicine
Private Companies
BIND Biosciences
Why: Targeting cancer drugs narrowly to tumor cells will improve efficacy and reduce the side effects of chemotherapy.
Key innovation: Its delivery system uses engineered nanoparticles to deliver drugs to specific cells.
Cellular Dynamics International
Why: Screening drugs on human heart cells will help researchers find treatments for cardiac problems and test drugs for toxic side effects.
Key innovation: Uses included pluripotent stems cells to make large numbers of heart cells for testing.
Claros Diagnostics
Why: Simple, fast diagnostic tests can help physicians track disease-related markers.
Key innovation: Its microfluidic device for doctors' offices can quickly detect elevated protein levels associated with prostate cancer.